Erectile dysfunction (ED) is one of the most common sexual problems that men deal with. There are a host of different causes of ED that range from nutrient deficiencies to clinical depression. It’s important to talk to a medical professional about ED, in order to determine the cause of the issue before exploring treatment options. That said, erectile dysfunction has been found in recent years to be a symptom of zinc deficiency.
Aside from pelvic floor exercises, it has been found out that aerobic exercises also work in treating erectile dysfunction. This condition is often caused by problems related to blood flow to the penis. Diabetes, obesity, vascular disease as well as high cholesterol may affect blood flow. This results to erectile dysfunction. By adding some aerobic exercises to your routine, you can significantly enhance your overall male sexual health and may even remove the problem totally in the long run.
Dr. Niket Sonpal is the Associate Program Director of the Internal Medicine Residency at Brookdale Hospital Medical Center in Brooklyn and an Associate Professor at Touro College of Osteopathic Medicine. He’s a practicing Gastroenterologist and Hepatologist with a focus on Men’s and Women’s Health, and a regular contributor to Women’s health, Shape and Prevention Magazine.

Despite the proven long-term efficacy of PDE5i, it has been suggested that tachyphylaxis to this therapy may develop. Long-term treatment with PDE5i and excessive cGMP accumulation may up-regulate PDE5 (El-Galley et al 2001). Such hypothesis however, has not been proven in the existing clinical trials with chronic PDE5i therapy (Behr-Roussel et al 2005; Musicki et al 2005). Currently, there are no evidence-based data to support tachyphylaxis in patients treated with sildenafil or any other PDE5i.
Since endothelial dysfunction, CVD and ED are closely associated in epidemiological studies, the question for clinicians is whether to recommend the man presenting with ED undergo a cardiovascular (CV) evaluation. Clearly, based on numerous studies, ED can be considered at least a ‘marker’ for possible further vascular disease or CVD.15 In their report, Vlachopoulos and coworkers make the point that the man presenting with ED, the clinician, is offered an opportunity to attempt to improve the health of the man by addressing lifestyle modification, and consider further vascular evaluation owing to the clear relationship between endothelial dysfunction, ED and CVD.19
This led to nausea, dizziness, hallucinations, and a five-day throbber that could have cost him his life. But you needn't take handfuls of the stuff for bad things to happen. In 2007, the wife of a 50-year-old Italian construction worker spiked her husband's wine with just two Viagra which resulted in him suffering a near-fatal heart attack. There are many other reports of people dying from a heart attack as a result of taking Viagra, but one gentleman nearly suffered a fate worse than death after trying to impress his wife by super-dosing. Gentil Ramírez Polanía, a Colombian farmer in his mid-60s scarfed a bunch of the stuff and impressed his woman with a multi-day hard on before checking himself into a hospital with an inflamed, fractured and gangrenous penis. Only emergency surgery managed to save Polanía's life and his penis although, sadly, it was not quite the same as it once was.
A number of nonprescription products claim to be herbal forms of Viagra. Some of these products contain unknown amounts of ingredients similar to those in prescription medications, which can cause dangerous side effects. Some actually contain the real drug, which should be given by prescription only. Although the Food and Drug Administration has banned many of these products, some potentially dangerous erectile dysfunction remedies remain on the market.
Lifestyle changes like getting more exercise and adjusting your diet can help. In a study of obese men with E.D. who restricted calories for two years and were advised to be more active, participants not only lost weight but also experienced decreased severity of their E.D. Research also shows aerobic exercise can significantly lower your risk of erectile dysfunction thanks to its ability to boost blood flow and circulation. Eating certain foods can also reduce incidence of E.D.

Cai, T., Verze, P., Massenio, P., Tiscione, D., Malossini, G., Cormio, L. ... Mirone, V. (2016, August 12). Rhodiola rosea, folic acid, zinc and biotin (EndEP®) is able to improve ejaculatory control in patients affected by lifelong premature ejaculation: Results from a phase I II study. Experimental and Therapeutic Medicine, 12(4), 2083-2087. Retrieved from https://www.spandidos-publications.com/10.3892/etm.2016.3595

If you are taking sildenafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medication any time from 4 hours to 30 minutes before sexual activity. Sildenafil usually should not be taken more than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take sildenafil less often. You can take sildenafil with or without food. However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work.


Three subsets (eight in each subset) of sexually experienced adult male rats were supplemented with three different oral doses of zinc sulphate (a daily dose of 1 mg, 5 mg and 10 mg respectively) for two weeks. A subset of eight animals without zinc supplementation was used as the control group Sexual behavior was observed by placing them individually in cages with receptive females.
"Erections are good for your penis, and probably good for mental health. Taking medication for erections may also be good for a man's overall health. This is the first study to look at long-term treatment to improve erectile function in men, but the sample is too small to definitively answer the question. We really need a big study with a long follow-up to know the answers." Mulhall, who was not involved in the study, is an associate professor and director of sexual medicine in the departments of urology at Weill Medical College of Cornell University and Memorial Sloan-Kettering Cancer Center in New York.

A glass of pomegranate juice a day keeps the oncologist away? Such may be the case if further evidence confirms a recent investigation of the pomegranate's ability to inhibit breast cancer cells. Previous studies have shown that pomegranate juice disrupts metastasis of breast and prostate cancers, but in a new study, researchers found that phytochemicals in pomegranate extract altered breast cancer stem cells, inhibiting cell growth and differentiation. Does this warrant more investigation? Find out here.

This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.


The problem with this though is that there are a lot of websites that are claiming to have a specific exercise technique or perhaps very effective male enhancement products that can guarantee erectile dysfunction. Be careful not to fall for a male enhancement scam. Even though erectile dysfunction may be stressful or difficult to discuss about, there are proven and safe methods that can help you in dealing with it.
The time to maximum plasma concentration is about 1 h while the plasma half-life is about 4–5 h. It is administered orally on demand in 25 mg, 50 mg, and 100 mg doses. The recommended starting dose is 50 mg and adapted according to efficacy and tolerability. Patients are instructed to take sildenafil approximately 1 h before sexual intercourse with a maximum dosing frequency of once daily. Sexual stimulation is a prerequisite for sildenafil as well as for the other PDE5i. The window of opportunity to engage in sexual intercourse is maintained from 30 min to 4–5 h from administration. However, the onset of action can be 14 min for about 35% of patients (Figure ​(Figure1)1) (Padma-Nathan et al 2003) and efficacy may be maintained for up to 12 h (Moncada et al 2004). A heavy fatty meal results in reduced and prolonged absorption. Alcohol does not have an impact on absorption in regular doses. Contraindications for the use of sildenafil and need for dose adjustments are summarized in Table ​Table11 (Langtry and Markham 1999).
Impotence, or erectile dysfunction (ED), is the inability for a man to sustain an erection long enough for normal, satisfying sexual intercourse.  To understand the underlying causes of impotence, it helps to know the basics about how an erection develops, along with potential problems that get in the way. Erections begin in the brain with a thought related to sexual desire. Then a chemical message travels from the brain to the penis. Blood flow to the penis increases as blood vessels leading to the reproductive system relax and allow for increased circulation.
E.D. may just be that early warning sign. Erections depend on blood flow, and blood flow depends on nice, wide-open arteries. Atherosclerosis doesn’t just affect the arteries around your heart; if you have plaque build-up, you are likely to have it all around the arterial system — and the penile artery is one of the smallest arteries you have (no matter what you claim about your size). So if you have atherosclerosis, then the plaque there will be one of the first places where you would notice a decline in blood flow.
Selenium, found in Brazil nuts, liver and oysters, is a trace mineral that plays an important role in hormone health. You only need a tiny bit for healthy sperm, but a tiny deficiency can be catastrophic for reproductive health. In one study, men who had lower testosterone and were infertile also had significantly lower selenium levels than the fertile group. Supplementing with the mineral improved chances of successful conception by 56 percent. And a second British Journal of Urology study that included 69 infertile men with low levels of the mineral, found selenium supplementation could significantly improve sub-par sperm motility associated with testosterone deficiency. Check out these 7 Testosterone-Boosting Foods!
Although they work in similar ways, each oral medication has a slightly different chemical makeup. These minor differences affect the way each medication works, such as how quickly it takes effect and wears off, and the potential side effects. Your doctor will consider these factors as well as any health problems you have and possible interactions with other medications you take.
The development of successful sexual behavior involves not only important neuroendocrine and local genital changes that begin at puberty, but also psychological and social influences that occur both before and after puberty.[7,8] Sexual behavior in males is regulated mainly by internal patterns of hormones; i.e. T, progesterone and PRL. These hormones are modulated by the male interactions with the social environment.[9]
Consider the case of Mr. Jones, a new patient I was helping in an ambulatory cardiac clinic. Most of my patients are on multiple medications for their heart conditions and other complicated issues, so I often review their medications to make sure everything is all right. This includes screening labs, checking vitals, reviewing past reports, and conducting drug interaction checks related to therapy. If there are any concerns, I’ll meet with the patient and make recommendations to the healthcare team.
However, our friend is not in fact some sort of unthinking, unfeeling sex bot and as such is going to have his resolve softened by a number of external factors such as the ones mentioned above. As Kerner says, Viagra can help with the non-physical hurdles in between him and a prize winning hard-on, and it's probably not going to do him any serious or permanent damage.

The number of intromissions in the 5 mg/day group was comparable with controls. On the other hand number of penile thrusting was significantly increased with the same dose. These are indications of unimpaired erectile function due to supplemented zinc. Our observations also confirmed the lack of aberrant sexual behavior which is indicative of uninhibited penile tactile sensations.[15] Sexual behavior may also be changed with motor weaknesses and incoordination.[12] Supplementation with zinc did not impair muscle strength or coordination when tested with bar and bridge tests, indicating that prolongation of ejaculation was not mediated through these mechanisms.
The next new treatments for erectile dysfunction will probably be improvements in some ED drugs already being used. "A dissolvable form of Levitra that you put under your tongue is coming that may work more quickly than the pills we have now," says Feloney. A new form of alprostadil may make it possible for you to rub it directly on the penis instead of inserting or injecting it. And newer phosphodiesterase inhibitors that last even longer and cause fewer side effects are being developed. Stay tuned!
Aerobic exercises and pelvic floor exercises are two of the best methods to start with. As a matter of fact, you can see improvements on your condition without having to witness the side effects of other male enhancement products. For one, there are certain male enhancement products which should not be taken if you are suffering from other types of medical condition. For instance, if the product contains substances that may react to the male enhancement ingredients of a product, you may suffer from certain consequences.
On the other hand, high zinc levels have negative effects on sperm quality. Excessive zinc intake in mice have indicated a negative effect of increasing doses of zinc on sperm count and motility.[5] Although there have been studies focusing on various aspects of zinc related reproductive functions, studies on zinc related sexual behavioral aspects have received scant attention. In one study, intranasal irrigation with zinc sulphate has been reported to completely abolish the sexual behavior of male rats.[6]

The prolongation of ejaculatory latency may be beneficial when present with unimpaired arousability, penile erection and sex vigor. The ejaculatory latency can also be prolonged due to some disorders in the neuroendocrine or reproductive system.[24] But the duration of zinc supplementation in our study was only two weeks which is not long enough to have an impact on the neuroendocrine or reproductive system.

Female rats were injected subcutaneously estradiol benzoate 12 μg in olive oil and 0.5 mg progesterone (Sigma chemicals, USA) in olive oil, 48 hrs and six hours prior to introduction to the males.[11] A cervical smear was observed under a light microscope and females in their estrous cycle were included in the study. Observations were performed during the dark phase of the day cycle (19.00 hours) under dim red light. After two hours of the last dose, rats were placed individually in transparent observation cages for 15 minutes adaptation period. A stimulus-receptive female was introduced to each male by gently dropping them in to the observation cage.


A man needs to try the medicine at least four times before he concludes that it doesn’t work for him. It is unlikely that a man with diabetes who has other medical problems such as high blood pressure, is taking multiple medicines, and has not had sexual intercourse for several years will be able to have an erection adequate for intercourse the first time he takes a pill. Most men need to try the medicine several times before they have the desired results.
To locate the muscles these exercises engage, try to stop and restart the flow of urine mid-stream. Just do this once, because if you do it too much it can affect the passage of urine. Once you’ve located these muscles, you can tighten and draw the muscles in, feeling them lift upward. Hold for a count of five, then release. It’s recommended that men do 8 to 10 repetitions, resting in between. Ideally, each series of 8 to 10 should be followed by 5 to 10 quick squeezes and releases, and men should work up to doing the whole process four or five times per day for best results.
Erectile function was also assessed using a standard scoring system. The researchers took factors such as height, weight, blood pressure, hand grip strength, amount of body fat, age, education, marital status, occupation and smoking behavior into account. Depression, the probability of obstructive sleep apnea, medication usage, diet and alcohol consumption, and physical activity were also assessed, as were blood levels of glucose, triglycerides (an unhealthy blood fat) and cholesterol.
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